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Independent Publications
Van Meter, E. N.*; Onyango, J.*; Teske, K. A., A Review of Currently Identified Small Molecule Modulators of microRNA Function. Eur. J. Med. Chem. 2020, 188, 112008 (*Shared authorship)
Publications: Publications
Postdoctoral Publications
Wen, J.; Teske, K. A.; Hadden, M. K., Inhibition of Hedgehog Signaling by Stereochemically Defined Des-Triazole Itraconazole Analogues. Bioorg. Med. Chem. Lett. 2019, 30, (2), 126794
Poe, M. M.; Agabiti, S. S.; Liu, C.; Li, V.; Teske, K. A.; Hsiao, C.-H. C.; Wiemer, A. J., Probing the ligand binding pocket of BTN3A1. J. Med. Chem. 2019, 62, 6814-6823
Pace, J. R.; Teske, K. A., Chau, L. Q.; Dash, R. C.; Zaino, A. M.; Wechsler-Reya, R. J.; Hadden, M. K., Structure-Activity Relationships for Itraconazole-Based Triazolone Analogues as Hedgehog Pathway Inhibitor. J. Med. Chem. 2019, 62, 3873-3885.
Teske, K. A.; Dash, R. C.; Morel, S. R.; Chau, L. Q.; Wechsler-Reya, R. J.; Hadden, M. K. Development of Posaconazole- Based Analogues as Hedgehog Signaling Pathway Inhibitors. Eur. J. Med. Chem. 2019, 163, 320-332.
Teske, K. A.; Hadden, M. K., Methyllysine Binding Domains: Structural Insight and Small Molecule Probe Development. Eur. J. Med. Chem. 2017, 136, 14-35.
Publications: Publications
Graduate Publications
Teske, K. A.; Bogart, J. W.; Arnold, L. A. Novel VDR antagonist based on the GW9742 scaffold. Bioorg. Med. Chem. Lett., 2018, 28, 351-354.
Teske, K. A.; Rai, G.; Nandhikonda, P.; Sidhu, Preetpal S. S.; Feleke, B.; Simeonov, A; Yasgar, A.; Jadjav, A.; Maloney, D.; Arnold, L. A., A Parallel Chemistry Approach to Identify Novel Nuclear Receptor Ligands Based on GW0742 Scaffold. ACS Comb. Sci., 2017, 19, 646-656.
Wang, Y.; Fan, H.; Balakrishnan, K.; Lin, Z.; Cao, S.; Chen, W.; Fan, Y.; Guthrie, Q.; Sun, H.; Teske, K. A.; Gandhi, V.; Arnold, L. A.; Peng, Peng, X., Hydrogen Peroxide Activated Quinone Methide Precursors with Enhanced DNA Cross-Linking Capability and Cytotoxicity Towards Cancer Cells. Eur. J. Med. Chem. 2017, 133, 197-207.
Poe, M. M.; Methuku, K. R.; Li, G.; Verma, A.; Teske, K. A.; Stafford, D. C.; Arnold, L. A.; Cramer, J. W.; Jones, T. M.; Cerne, R.; Krambis, M. J.; Witkin, J. M.; Jambrina, E.; Rehman, S.; Ernst, M.; Cook, J. M.; Schkeryantz, J. M., Synthesis and Characterization of a Novel GABAA Receptor Ligand that Combines Outstanding Metabolic Stability, Pharmacokinetics and Anxiolytic Activity. J. Med, Chem. 2016, 23, 10800-10806
Teske, K. A.; Bogart, J. W.; Sanchez, L. M.; Yu, O. B.; Preston, J. V.; Cook, J. M.; Silvaggi, N. R.; Bikle, D. D.; Arnold, L. A., Synthesis and Evaluation of Vitamin D Receptor-Mediated Activities of Cholesterol and Vitamin D Metabolites. Eur. J. Med. Chem. 2016, 109, 238-46
Teske, K. A.; Yu, O.; Arnold, L. A., Inhibitors of the Vitamin D Receptor-Coregulator Interaction. In Vitamin D Hormone, 2016; Vol. 100, pp 45-82.
Guthrie, M. L.; Sidhu, P. S.; Hill, E. K.; Horan, T. C.; Nandhikonda, P.; Teske, K. A.; Yuan, N. Y.; Sidorko, M.; Kodali, R.; Cook, J. M.; Han, L.; Silvaggi, N. R.; Bikle, D. D.; Moore, R. G.; Singh, R. S.; Arnold, L. A., Anti-tumor Activity of 3-Indoylmethanamines 31B and PS121912. Anticancer Research 2015, 35.
Sidhu, P. S.; Teske, K.; Feleke, B.; Yuan, N. Y.; Guthrie, M. L.; Fernstrum, G. B.; Vyas, N. D.; Han, L.; Preston, J.; Bogart, J. W.; Silvaggi, N. R.; Cook, J. M.; Singh, R. K.; Bikle, D. D.; Arnold, L. A., Anticancer Activity of VDR-Coregulator Inhibitor PS121912. Cancer Chemother Pharmacol 2014.
Teske, K.; Nanhikonda, P.; Bogart, J. W.; Feleke, B.; Sidhu, P.; Yuan, N. Y.; Preston, J.; Goy, R.; Han, L.; Silvaggi, N. R.; Singh, R. K.; Bikle, D. D.; Cook, J. M.; Arnold, L. A., Identification of VDR Antagonists Among Nuclear Receptor Ligands Using Virtual Screening. Nuclear Receptor Research 2014, 1, 1-8.
Teske, K.; Nandhikonda, P.; Bogart, J. W.; Feleke, B.; Sidhu, P.; Yuan, N.; Preston, J.; Goy, R.; Arnold, L. A., Modulation of Transcription Mediated by the Vitamin D Receptor and the Peroxisome Proliferator-Activated Receptor δ. Biomolecular Research & Therapeutics 2014, 3 (1).
Sidhu, P. S.; Nassif, N.; McCallum, M. M.; Teske, K.; Feleke, B. D.; Yuan, N. Y.; Nandhikonda, P.; Cook, J. M.; Singh, R. K.; Bikle, D. D.; Arnold, L. A., Development of Novel Vitamin D Receptor-Coactivator Inhibitors. ACS Medicinal Chemistry Letters 2014, 5 (2), 199-204.
Nandhikonda, P.; Yasgar, A.; Baranowski, A.; Sidhu, P. S.; McCallum, M. M.; Pawlak, A. J.; Teske, K.; Feleke, B.; Yuan, N. Y.; Kevin, C.; Bikle, D. D.; Ayers, S. D.; Webb, P.; Rai, G.; Simeonov, A.; Jadhav, A.; Maloney, D.; Arnold, L. A., Peroxisome Proliferation- Activated Receptor δ Agonist GW0742 Interacts Weakly with Multiple Nuclear Receptors, Including the Vitamin D Receptor. Biochemistry 2013, 52, 4193-4203.
Publications: Publications
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